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TissueArray.com LLC ffpe bone core slides catalog #t261b
PSMA is detected on the vasculature of GCTB. (A, B) Representative hematoxylin and eosin staining of an <t>FFPE</t> bone biopsy core from a 20-year-old male with clinically diagnosed GCTB. Arrows point to multinucleated giant cells that are a hallmark of GCTB (black arrows). (C, D) IHC of an FFPE bone biopsy from a 20-year-old male with GCTB is positive for PSMA, as visualized by the brown precipitate and black arrows. Multinucleated giant cells counterstained with hematoxylin can be identified within the section (circled in red). (E) IF staining of PSMA (red), CD31 (green), and the nucleus (blue, DAPI). White arrows indicate examples of Co-localization. (F) Pearson correlation coefficient (r) as measured by Zeiss Zen software. The intensity of a given pixel in the CD31 image is used as the y-coordinate of the scatter plot, and the intensity of the corresponding pixel in the PSMA is the x-coordinate. (G) Cancer adjacent normal bone and bone marrow tissue (NAT) of rib containing a layer of adipocytes adjacent to bony trabeculae and red blood cells were used as negative controls and is void of PSMA staining. (H) IF staining of NAT negative control for PSMA (red) and CD31 (green), nuccleus (blue, DAPI) (20x, scale bar = 50μM). N=28 GCTB patient bone core samples, N=9 NAT controls. The immunofluorescence and immunohistochemistry images, as well as the co-localization information for all 28 patients and negative controls, can be found in <xref ref-type= Supplementary Figures 1 3 . All tissue in this figure was purchased from MicroArray.Com, and further information about the tissue can be found in Materials and Methods. Hematoxylin and eosin images are from TissueArray.Com . " width="250" height="auto" />
Ffpe Bone Core Slides Catalog #T261b, supplied by TissueArray.com LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ffpe bone core slides catalog #t261b/product/TissueArray.com LLC
Average 90 stars, based on 1 article reviews
ffpe bone core slides catalog #t261b - by Bioz Stars, 2026-03
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TissueArray.com LLC gctb patient bone core formalin-fixed paraffin-embedded (ffpe) slides
PSMA is detected on the vasculature of GCTB. (A, B) Representative hematoxylin and eosin staining of an <t>FFPE</t> bone biopsy core from a 20-year-old male with clinically diagnosed GCTB. Arrows point to multinucleated giant cells that are a hallmark of GCTB (black arrows). (C, D) IHC of an FFPE bone biopsy from a 20-year-old male with GCTB is positive for PSMA, as visualized by the brown precipitate and black arrows. Multinucleated giant cells counterstained with hematoxylin can be identified within the section (circled in red). (E) IF staining of PSMA (red), CD31 (green), and the nucleus (blue, DAPI). White arrows indicate examples of Co-localization. (F) Pearson correlation coefficient (r) as measured by Zeiss Zen software. The intensity of a given pixel in the CD31 image is used as the y-coordinate of the scatter plot, and the intensity of the corresponding pixel in the PSMA is the x-coordinate. (G) Cancer adjacent normal bone and bone marrow tissue (NAT) of rib containing a layer of adipocytes adjacent to bony trabeculae and red blood cells were used as negative controls and is void of PSMA staining. (H) IF staining of NAT negative control for PSMA (red) and CD31 (green), nuccleus (blue, DAPI) (20x, scale bar = 50μM). N=28 GCTB patient bone core samples, N=9 NAT controls. The immunofluorescence and immunohistochemistry images, as well as the co-localization information for all 28 patients and negative controls, can be found in <xref ref-type= Supplementary Figures 1 3 . All tissue in this figure was purchased from MicroArray.Com, and further information about the tissue can be found in Materials and Methods. Hematoxylin and eosin images are from TissueArray.Com . " width="250" height="auto" />
Gctb Patient Bone Core Formalin Fixed Paraffin Embedded (Ffpe) Slides, supplied by TissueArray.com LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/gctb patient bone core formalin-fixed paraffin-embedded (ffpe) slides/product/TissueArray.com LLC
Average 90 stars, based on 1 article reviews
gctb patient bone core formalin-fixed paraffin-embedded (ffpe) slides - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

90
TissueArray.com LLC ffpe bone core slides
PSMA is detected on the vasculature of GCTB. (A, B) Representative hematoxylin and eosin staining of an <t>FFPE</t> bone biopsy core from a 20-year-old male with clinically diagnosed GCTB. Arrows point to multinucleated giant cells that are a hallmark of GCTB (black arrows). (C, D) IHC of an FFPE bone biopsy from a 20-year-old male with GCTB is positive for PSMA, as visualized by the brown precipitate and black arrows. Multinucleated giant cells counterstained with hematoxylin can be identified within the section (circled in red). (E) IF staining of PSMA (red), CD31 (green), and the nucleus (blue, DAPI). White arrows indicate examples of Co-localization. (F) Pearson correlation coefficient (r) as measured by Zeiss Zen software. The intensity of a given pixel in the CD31 image is used as the y-coordinate of the scatter plot, and the intensity of the corresponding pixel in the PSMA is the x-coordinate. (G) Cancer adjacent normal bone and bone marrow tissue (NAT) of rib containing a layer of adipocytes adjacent to bony trabeculae and red blood cells were used as negative controls and is void of PSMA staining. (H) IF staining of NAT negative control for PSMA (red) and CD31 (green), nuccleus (blue, DAPI) (20x, scale bar = 50μM). N=28 GCTB patient bone core samples, N=9 NAT controls. The immunofluorescence and immunohistochemistry images, as well as the co-localization information for all 28 patients and negative controls, can be found in <xref ref-type= Supplementary Figures 1 3 . All tissue in this figure was purchased from MicroArray.Com, and further information about the tissue can be found in Materials and Methods. Hematoxylin and eosin images are from TissueArray.Com . " width="250" height="auto" />
Ffpe Bone Core Slides, supplied by TissueArray.com LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ffpe bone core slides/product/TissueArray.com LLC
Average 90 stars, based on 1 article reviews
ffpe bone core slides - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

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PSMA is detected on the vasculature of GCTB. (A, B) Representative hematoxylin and eosin staining of an FFPE bone biopsy core from a 20-year-old male with clinically diagnosed GCTB. Arrows point to multinucleated giant cells that are a hallmark of GCTB (black arrows). (C, D) IHC of an FFPE bone biopsy from a 20-year-old male with GCTB is positive for PSMA, as visualized by the brown precipitate and black arrows. Multinucleated giant cells counterstained with hematoxylin can be identified within the section (circled in red). (E) IF staining of PSMA (red), CD31 (green), and the nucleus (blue, DAPI). White arrows indicate examples of Co-localization. (F) Pearson correlation coefficient (r) as measured by Zeiss Zen software. The intensity of a given pixel in the CD31 image is used as the y-coordinate of the scatter plot, and the intensity of the corresponding pixel in the PSMA is the x-coordinate. (G) Cancer adjacent normal bone and bone marrow tissue (NAT) of rib containing a layer of adipocytes adjacent to bony trabeculae and red blood cells were used as negative controls and is void of PSMA staining. (H) IF staining of NAT negative control for PSMA (red) and CD31 (green), nuccleus (blue, DAPI) (20x, scale bar = 50μM). N=28 GCTB patient bone core samples, N=9 NAT controls. The immunofluorescence and immunohistochemistry images, as well as the co-localization information for all 28 patients and negative controls, can be found in <xref ref-type= Supplementary Figures 1 3 . All tissue in this figure was purchased from MicroArray.Com, and further information about the tissue can be found in Materials and Methods. Hematoxylin and eosin images are from TissueArray.Com . " width="100%" height="100%">

Journal: Frontiers in Oncology

Article Title: Repurposing of PSMA-targeted diagnostic and therapeutic agents for the detection and treatment of giant cell tumors of bone

doi: 10.3389/fonc.2024.1504514

Figure Lengend Snippet: PSMA is detected on the vasculature of GCTB. (A, B) Representative hematoxylin and eosin staining of an FFPE bone biopsy core from a 20-year-old male with clinically diagnosed GCTB. Arrows point to multinucleated giant cells that are a hallmark of GCTB (black arrows). (C, D) IHC of an FFPE bone biopsy from a 20-year-old male with GCTB is positive for PSMA, as visualized by the brown precipitate and black arrows. Multinucleated giant cells counterstained with hematoxylin can be identified within the section (circled in red). (E) IF staining of PSMA (red), CD31 (green), and the nucleus (blue, DAPI). White arrows indicate examples of Co-localization. (F) Pearson correlation coefficient (r) as measured by Zeiss Zen software. The intensity of a given pixel in the CD31 image is used as the y-coordinate of the scatter plot, and the intensity of the corresponding pixel in the PSMA is the x-coordinate. (G) Cancer adjacent normal bone and bone marrow tissue (NAT) of rib containing a layer of adipocytes adjacent to bony trabeculae and red blood cells were used as negative controls and is void of PSMA staining. (H) IF staining of NAT negative control for PSMA (red) and CD31 (green), nuccleus (blue, DAPI) (20x, scale bar = 50μM). N=28 GCTB patient bone core samples, N=9 NAT controls. The immunofluorescence and immunohistochemistry images, as well as the co-localization information for all 28 patients and negative controls, can be found in Supplementary Figures 1 3 . All tissue in this figure was purchased from MicroArray.Com, and further information about the tissue can be found in Materials and Methods. Hematoxylin and eosin images are from TissueArray.Com .

Article Snippet: Commercial clinically diagnosed, deidentified, and coded FFPE bone core slides (TissueArray.com, catalog #BO601, #BO801, and #T261b) were deparaffinized and rehydrated.

Techniques: Staining, Software, Negative Control, Immunofluorescence, Immunohistochemistry, Microarray